Polynucleotides

Service Description

Polynucleotides (PN) are highly purified, biocompatible DNA fragments derived most commonly from salmon DNA. Their structure mimics natural human DNA, allowing them to safely integrate into the skin’s extracellular environment. In regenerative aesthetics, polynucleotides act as bio-revitalising agents, stimulating deep tissue repair, hydration, and collagen production — ideal for patients seeking natural, non-volumising rejuvenation. 🔬 Mechanism of Action Polynucleotides work by: -Deep Hydration: They attract and bind water molecules, increasing skin moisture from within. -Cellular Regeneration: Stimulate fibroblast activity and tissue remodeling. -Antioxidant Protection: Neutralise free radicals and reduce inflammation. -Collagen and Elastin Synthesis: Promote long-term structural improvement in skin tone and elasticity. -DNA Repair Support: Encourage natural cell renewal and healing. 🌿 Aesthetic Indications -Periorbital rejuvenation (dark circles, crepey skin, fine lines) -Facial laxity or loss of tone -Acne scarring and enlarged pores -Neck and décolleté tightening -Skin damaged by sun, pollution, or medical treatments -Pre- and post-procedure dermal support (e.g., microneedling, peels, lasers) 🧪 Popular Polynucleotide Brands Vitaran = Think hydration, glow, prevention → perfect for younger or first-time patients Nucleofill = Think lifting, structural repair, deeper rejuvenation → better for mature or tired skin 📅 Treatment Protocol Initial Course: -3–4 sessions, spaced 2 to 4 weeks apart (based on skin concern and product used). -For under-eye or delicate areas, lower volumes and slower schedules may apply. Maintenance: -1 session every 4 to 6 months to sustain results and prevent regression. Technique: ▸ Injected intradermally using micro-needles ⏳ Results Timeline Immediately Mild plumping, hydration, and improved skin comfort 1–2 weeks Brighter skin tone, subtle texture improvement 3–4 weeks Visible reduction in fine lines, firmer feel, more uniform complexion 6–8 weeks Full regenerative effect: enhanced elasticity, fewer wrinkles, more radiant skin Ongoing Improved resilience to environmental stress and slower skin ageing ⚠️ Contraindications -Pregnancy or breastfeeding -Active skin infections or cold sores -Autoimmune or clotting disorders -Hypersensitivity to fish-derived products